
Folic acid capsules - with Quatrefolic, the effective, active form of folate
Vitality Nutritionals BioActive Folate 400 µg capsules are ideal for basic folate supply or for targeted, individual support of the folate balance.
Natural, bioactive form of folic acid
Highest bioavailability and bioactivity
Highly dosed with 900 mcg Quatrefolic
Easy to swallow plant-based capsules
Guaranteed pure and free of additives
Very well tolerated and vegan
BioActive Folate contains patented Quatrefolic, the bioactive, stable form of folate in the form of 5-methyltetrahydrofolate (5-MTHF). This form of folate is immediately available and usable for the body.
It is more effective than conventional folic acid because it can perform its tasks directly without having to be first converted into active folate.
A single Vitality Nutritionals BioActive Folate 400 µg capsule contains
"Folate is the natural form of the vitamin that can be found in the body and in food and is composed of various physiological compounds. The industrially manufactured form is called folic acid and is used to fortify foods and vitamin supplements." (dge.de) [1]
Both folates and folic acid must first be converted into the active folate form 5-MTHF in the body in order to be used by the body's cells.
As a stable 5-methyltetrahydrofolate (5-MTHF), Quatrefolic® is both highly bioavailable and bioactive: It can be directly absorbed and used by the body without first having to be converted into active folate in the body.
Result of extensive research
To make 5-MTHF, the bioactive form of folate, directly available to the body through a dietary supplement, it must be stabilized. After years of research, an Italian manufacturer succeeded in doing this by binding the folate to plant-based glucosamine. The result? Quatrefolic®, currently the most effective stable form of folate with maximum bioavailability.
Quatrefolic® enters the bloodstream via the small intestine and is then absorbed directly into the cells without first having to be converted in the body, as is the case with typical folic acid or folate from food. The folate absorbed via Quatrefolic® in the form of 5-MTHF can thus immediately fulfill its important metabolic tasks.
Quatrefolic® is also the only form of folic acid that can cross the blood-brain barrier and also have an effect in the brain. Scientists assume that a folic acid deficiency in the brain is a risk factor for developing mood swings or forgetfulness.
Ingredients
Bulking Agent: Acacia Gum, Coating Agent: Hydroxypropylmethyl Cellulose (capsule), Folate (as Quatrefolic® [6S]-5-Methyltetrahydro-Folate Glucosamine Salt)
Allergens
This product contains no allergens.
Nutrition facts
Recommended daily dose: 1 capsule
Amount per daily dosage
|
|
Amount (% NRV*) per 1 capsule |
|---|---|
|
Quatrefolic® of which bioactive Folate |
900 µg 400 µg (200%*) |
* % of NRV (Nutrient Reference Value) according to EU regulation
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Vitality Nutritionals formulations are free from impurities, articial flavourings and artificial sweeteners. Vegan or vegetarian ingredients are used where possible, and every product is non-GMO.
BioActive Folate 400 µg - guaranteed
The following information has been scientifically studied and confirmed by the European Food Safety Authority (EFSA). [2]
Folate and/or folic acid are also known as vitamin B9 and are one of the essential B vitamins. Folic acid is only found in our diet in the form of folate. It is mainly found in green leafy vegetables, sprouts, fruits, nuts, dairy products, egg yolks, and liver.
However, folates are not very stable, and about 60-90% of folate is destroyed during cooking and through exposure to light. As a result, even nutrition-conscious people often find it difficult to meet their folate need through diet alone.
On top of that, only about 50% of the folate that makes its way into the body is absorbed. The reason for this is that enzymatic processes in the small intestine must first reduce folate to 5-methyltetrahydrofolate (5-MTHF). Only in this form it can be transported in the blood and perform its tasks in tandem with other vitamins such as B12 and B6.
Folic acid is primarily offered as a nutritional supplement since, to date, it has not been possible to stabilise folate. But even folic acid must first be converted in the body into the active form of folate-5-MTHF, so that it can be used by our cells.
by eating a balanced diet. However, achieving this may not always be feasible - either temporarily or permanently.
Folates are not very stable and around 60 to 90% of the folate in food is destroyed during cooking or by exposure to light. In addition, stress and certain illnesses, for example, can result in higher folic acid requirements. Even nutrition-conscious people often find it difficult to cover their folate and folic acid requirements with food.
Pregnant women, women looking to conceive and women who are not using contraception are expressly recommended to take folic acid supplements to ensure an adequate supply in pregnancy – be it planned or unplanned. [3]
It can therefore be sensible to ensure optimal folate or folic acid intake by taking appropriate dietary supplements.
"Food supplements are effective when the right nutrients are consumed by appropriate individuals at the right time and in the correct amounts." (verbraucherzentrale.de) [4]
Vitality Nutritionals BioActive Folate 400 µg capsules are ideal for providing overall support for maintaining the folate balance, especially for those with an increased need for folate:
As previously mentioned, folic acid or folate obtained from food must first be converted by the body into the active folate form 5-MTHF. However, roughly half of all individuals have reduced enzyme function due to a genetic defect, the so-called MTHFR mutation, which can be detected through a gene test.
If the necessary enzymes are missing, unmetabolised conventional folic acid cannot be converted into the active folate 5-MTHF. Since 5-MTHF also activates the inactive form of vitamin B12 - Cobalamin - the presence of this genetic defect also impairs all vitamin B12 metabolism.
This explains why, despite adequate intake of folic acid, some individuals' folate blood levels are too low and they also show symptoms of vitamin B12 deficiency. Therefore, these individuals require the active form of folic acid contained in BioActive Folate capsules, as well as active vitamin B12 in the form of methyl cobalamin.
The absorption of food-derived folate and folic acid can also be diminished by absorption deficiencies in the intestine caused by e.g. celiac disease, medications, or contraceptives.
Folic acid supplements are not suitable for
According to the latest findings, a high intake of folates, which naturally occur in food, is not harmful. In contrast, a high intake of folic acid, e.g. via food supplements or fortified foods, can be harmful if the recommended intake is exceeded.
According to the European Food Safety Authority (EFSA), the tolerable upper intake level for adults is 1000 µg of folic acid per day. For children and adolescents aged 1 to 17 years, the tolerable upper intake level is 200 to 800 µg per day. If the folic acid intake is higher over a longer period of time, the risk of adverse effects is increased. [5]
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?When it comes to your health, quality and safety are of the highest importance. Vitality Nutritionals has rigorous standards in place to ensure they work with only the most reputable suppliers.
View laboratory test results
How to use
The recommended intake is:
1 Capsule
Once per day
Usage
Take 1 capsule daily with a meal or as recommended by your physician.
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